Updated: Apr 8, 2022
The power-horse supplement
Injection IM: 20 mg/mL - 1 mL injection 1-2 times weekly.
Injection recommended because intestinal absorption of dietary CoQ10 is extremely limited and only consistent ingestion of large doses increase CoQ10 concentrations, especially in heart and brain mitochondria.
Increased athletic performance
Promotes cell protection by neutralizing free radicals
Reduces oxidative stress
Showed to reduce migraines by as much as 50%
Slows progression of Alzheimer's Disease
Improves fat burning
Preserves brain structure and slows neurodegeneration
Promotes anti-aging and is essiential in healthy aging
Fibromyalgia patients showed a significant reduction in symptoms following treatment
Improved muscle endurance, less fatigue during daily duties, and decreased serum lactate and pyruvate levels (in trials with patients with mitochondrial myopathy)
Improves symptoms in heart related disorders (cardiomyopathy and hypertension)
direct anti-atherogenic effect, meaning prevents the build up of fats in the arteries
In breast cancer patients 390 mg CoQ10 daily resulted in tumor regression and disappearance of previously diagnosed metastasis
Positive effect on Parkinson's Patients symptoms
Prevents fetal wasting in pregnant women
Safe even at high doses
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Buy research CoEnzyme Q10 from USA here.
Coenzyme Q10 is also called Ubiquinone, it is a powerful coenzyme that is responsible for increasing the body’s natural performance and stamina. CoQ10 is a naturally occurring fat-soluble quinone, it’s greatest natural concentration is within the mitochondria. Found to support energy production and athletic performance, skin appearance, and improved cognition. Other studies are determining the efficiency to support the treatment of cancer, mitochondrial diseases and heart disease.
Mechanism of Action
Coenzyme Q10 is a vitamin like nutrient that as determined in 1978 Nobel prize winning chemistry, helps convert food into energy. It also improves the heart, skeletal muscles, liver and brain. Q10 naturally boosts the release of human growth hormone (HGH) that puts the body into fat-loss and muscle building state. The heart has high energy demands and it was also found to contain high levels of Q10. Various studies have related coenzyme Q10 deficiency to heart disease.
low blood pressure
CoQ10 is a strong antioxidant. It has been determined that CoQ10 levels decrease with age and therefore CoQ10 deficiency could be a factor in development of chronic diseases. A study by López-Lluch et al., 2010, suggests that maintaining functional levels of CoQ10, could be a key factor in healthy aging.
A study conducted by Rozen et al. (2002) hypothesized that impaired energy metalbolism present in the brains of migraine sufferers could be treated with CoQ10. They found after 3 months of treatment (150mg/day) an overall 50% reduction in the frequency of migraine patients.
CoQ10 lowers blood pressure. Theorized to preserve nitric oxide which relaxes peripheral arteries, and thereby lowers the blood pressure. Hypertension, in some cases, is thought to be overproduction of superoxide radicals that inactivate nitric oxide. CoQ10, with its antioxidant effects, upsets this process and relieves hypertension in some. CoQ10 may also boost prostaglandin prostacyclin production, which is a potent vasodilator and inhibitor of platelet aggregation, also reducing blood pressure. Rosenfeldt et al., 2007, analyzed many clinical trials that investigated the use of CoQ10 for hypertension and determined it to be overall efficient at treating hypertension along with high blood pressure.
In other studies CoQ10 has been investigated in the treatment of cardiovascular diseases including heart failure. Heart failure has been has been associated with low CoQ10 levels, and is characterized by a loss of contractile function due to an energy depletion status in the mitochondria. Folkers et al., 1985b correlated a deficiency of CoQ10 to cardiomyopathy where endgoenous levels of CoQ10 correlated strongly with severity of the disease. This suggests CoQ10 treatment could be beneficial to patients. Langsjoen et al. [1994a] summarized 8 years of research on the benefits of CoQ10 in cardiology, including heart failure and myocardiopathy. They found that CoQ10 supplementation improved cardiovascular function via enhanced energy production, improved contractility of cardiac muscles, and its potent antioxidant activity, particularly the prevention of low-density lipoproteins oxidation. This proved that CoQ10 was beneficial in treating many heart diseases.
Rosenfeldt FL, Haas SJ, Krum H, Hadj A, Ng K, et al. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum Hypertens. 2007;21:297–306. [PubMed] [Google Scholar]
Prakash et al., 2010 found that increasing the concentration of CoQ10 by supplementation effectively suppressed advanced periodontal inflammation by reducing free radicals and reactive oxygen species.
Garrido-Maraver, Juan et al. “Coenzyme q10 therapy.” Molecular syndromology vol. 5,3-4 (2014): 187-97. doi:10.1159/000360101
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